E140: LK-99, Sclerotic establishments, Fitch downgrades US debt, Trump indicted... again

(0:00) Bestie intros! (0:53) LK-99 breakdown (24:39) Funding landscape for breakthrough science, sclerotic establishments, boomer incumbents (46:04) Fitch downgrades US debt rating (1:09:12) Trump's newest indictment Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://arxiv.org/ftp/arxiv/papers/2307/2307.12008.pdf https://arxiv.org/pdf/2307.12037.pdf https://manifold.markets/QuantumObserver/will-the-lk99-room-temp-ambient-pre?r=RWxpZXplcll1ZGtvd3NreQ https://twitter.com/667keos/status/1686490898480173056 https://twitter.com/iris_IGB/status/1685731177523449856 https://twitter.com/VCBrags/status/1684591950387716097 https://stanforddaily.com/2023/07/19/stanford-president-resigns-over-manipulated-research-will-retract-at-least-3-papers https://www.socialcapital.com/ideas/2021-annual-letter https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext https://www.bloomberg.com/news/articles/2023-07-24/sam-altman-valley-vcs-bet-48-million-on-blood-testing-startup https://www.fitchratings.com/research/sovereigns/fitch-downgrades-united-states-long-term-ratings-to-aa-from-aaa-outlook-stable-01-08-2023 https://www.npr.org/2023/08/02/1178215888/fitch-downgrade-credit-rating-deficits-debt-economy https://twitter.com/BillAckman/status/1686906272937869312 https://home.treasury.gov/news/press-releases/jy1670 https://www.washingtonpost.com/business/2023/07/22/gop-social-security-trump-rivals-cuts https://www.commondreams.org/news/republicans-cut-social-security https://sgp.fas.org/crs/misc/RS22331.pdf https://fred.stlouisfed.org/series/MORTGAGE30US https://fred.stlouisfed.org/series/UNRATE https://fred.stlouisfed.org/series/JTSJOL